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Multifunctional RNA engineering platform CREST published at NAR!

 July 3, 2023 |   |  Publications |  

Our work led by Graduate Student Zukai Liu now online at Nucleic Acids Research!
The CREST platform is a molecular operating system for RNA molecules that allows multitasking RNA-level operation
Check out the paper here: https://doi.org/10.1093/nar/gkad547

  Category: Publications

8 posts
July 3rd, 2023

Multifunctional RNA engineering platform CREST published at NAR!

Our work led by Graduate Student Zukai Liu now online at Nucleic Acids Research! The CREST platform is a molecular […]
July 21st, 2022

JACKIE gRNA design software and database published at The CRISPR journal

JACKIE software/database for gRNA designs is now published at The CRISPR Journal: https://doi.org/10.1089/crispr.2022.0042 For more information source code, database and […]
December 31st, 2021

Hot off the press: TALE.Sense published at ACS Synthetic Biology

Congrats to Aziz for his new publication at ACS synthetic biology! We created TALE-based in vivo DNA sensor components for […]
December 3rd, 2021

Published on Cancer Discovery, Casilio-based imaging method “ecTag” tracks ecDNA in live cancer cells.

In a collaboration with Roel Verhaak laboratory, we applied Casilio’s imaging modules to label unique breakpoint sequence on ecDNAs, allowing […]
September 16th, 2020

New paper on collaboration with Lau lab on 3D epigenome of C11or95-RELA+ ependymoma published in Acta Neuropathologica!

Check out our paper using different NGS technologies to profile 3D genome interactome, epigenome, transcriptome, and genome-wide binding by C11orf95-RELA […]
March 8th, 2020

Breakthrough in genomic imaging with Casilio and PISCES

Only one gRNA needed for #CRISPR live-cell non-repeat genomic imaging 🔬with #Casilio and PISCES – Multiple probes placed along a […]
February 28th, 2020

New Preprint: JACKIE: Fast enumeration of single- and multi-copy CRISPR binding sites

New preprint is now online at BioRxiv describing a software for enumerating potential CRISPR binding sequences, their copy numbers and […]
November 6th, 2019

Two papers published at Nature Communications within two months!

Two stories describing two new tech developed in the lab are online at Nature Communications. First paper (10.1038/s41467-019-12339-7), published in […]