Casilio: a versatile CRISPR-Cas9-Pumilio hybrid for gene regulation and genomic labeling

Cheng LabCRISPR/Cas + TALENEpigeneticsRepresentativeRNA Splicing + RBPsSynthetic Biology + Genome Engineering
Albert W Cheng*#, Nathaniel Jillette*, Phoebe Lee, Dylan Plaskon, Yasuhiro Fujiwara, Wenbo Wang, Aziz Taghbalout, Haoyi Wang*#
Cell Research 26:254–257. doi:10.1038/cr.2016.3
Publication year: 2016

Muscleblind-like 1 (Mbnl1) regulates pre-mRNA alternative splicing during terminal erythropoiesis

PhDEraRepresentativeRNA Splicing + RBPs
Albert W Cheng*, Jiahai Shi*, Piu Wong*, Katherine L Luo, Paula Trepman, Eric T Wang, Heejo Choi, Christopher B Burge, Harvey F Lodish
Blood 124(4):598-610
Publication year: 2014

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

Cancer + MetastasisPhDEraRNA Splicing + RBPs
Katz Y, Li F, Lambert NJ, Sokol ES, Tam WL, Cheng AW, Airoldi EM, Lengner CJ, Gupta PB, Yu Z, Jaenisch R, Burge CB
Elife 3:e03915
Publication year: 2014

Alternatively spliced mRNA isoforms as prognostic indicators for metastatic cancer

Cancer + MetastasisPatentsPhDEraRepresentativeRNA Splicing + RBPs
Christopher Boyce BURGE, Wu Albert CHENG, John S. Condeelis, Frank B. Gertler, Maja H. OKTAY, Irina M. SHAPIRO
WO2012116248 A1
Publication year: 2012

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

Cancer + MetastasisPhDEraRepresentativeRNA Splicing + RBPs
Irina M. Shapiro*, Albert W. Cheng*, Nicholas C. Flytzanis, Michele Balsamo, John S. Condeelis, Maja H. Oktay, Christopher B. Burge , Frank B. Gertler
PLoS Genet 7(8): e1002218
Publication year: 2010